TDMx for Amikacin

Model-Informed Precision Dosing

TDMxRUI v1.0.2 TDMxR v0.3.3

Disclaimer

TDMx is an educational tool and has been created for personal use only. The use of any result generated by TDMx is in any case the sole risk and responsibility of the TDMx user. The information provided by TDMx does not replace clinical judgement. Although TDMx has been validated carefully, there is no guarantee for the accuracy of the provided results. TDMx Amikacin has not been registered as a medical device; dosing decisions should not solely rely on TDMx and remain the responsibility of the treating physician.

When using TDMx, you automatically agree with this disclaimer and the legal notices.

Information for Users

TDMx is a reasearch project — your feedback helps us improve TDMx.

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Resources

Legal Notices User Manuals R Foundation

Regulatory

2026 Prof. Dr. Sebastian G. Wicha
Institute of Pharmacy,
University of Hamburg, Germany

Patient Record

Patient ID

Date of Birth

Dose Optimisation

Optimisation type

First dose Add dose

Dose optimisation is unavailable for a first dose in Model averaging mode - it would erase the TDM measurements Model averaging needs. Switch to Single Model, or enter TDM data first.

Patient File

Load Patient

Reference Time

Use current time

Use historic time

Single Model

Options

Population (PRED) Individual (IPRED) Variability

Resolution

HD SD

Download Table Report

Simulation Resolution

HD Resolution [hrs]

SD Resolution [hrs]

Treatment Duration Limit

Max. simulated duration [weeks]

Monte Carlo Simulations

Prediction interval method:

Delta-Method Monte Carlo

Replicates for visualisation

Replicates for dose prediction intervals

Variability components in MC simulation:

Inter-individual Inter-occasion Residual

Model Averaging

Averaging/selection criterion:

PK Table Colour Coding

Reference ranges used to colour-code target columns (green/red) in the PK table.

Shareable link with patient data encoded in URL: